Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 20/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL991468 | 0.95 | GRM5 (0.75) | GRM5 | |
| SCHEMBL990864 | 0.95 | GRM5 (0.75) | GRM5 | |
| SCHEMBL991001 | 0.95 | GRM5 (0.75) | GRM5 | |
| SCHEMBL27743703 | 0.88 | GRM5 (0.69) | GRM5 | |
| SCHEMBL990984 | 0.87 | GRM5 (0.74) | GRM5 | |
| SCHEMBL989740 | 0.86 | GRM5 (1.00) | GRM5 | |
| SCHEMBL3418213 | 0.86 | GRM5 (1.00) | GRM5 | |
| SCHEMBL989743 | 0.86 | GRM5 (1.00) | GRM5 | |
| SCHEMBL990300 | 0.84 | GRM5 (1.00) | GRM5 | |
| SCHEMBL991624 | 0.84 | GRM5 (1.00) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101321731-A | Nicotinic acid derivatives as metabotropic glutamate receptor modulators | NOVARTIS AG (CH) | 2008-12-10 | — | — | CN | disclosed |