SCHEMBL2877635

SCHEMBL2877635

CCCCOP(=O)(OCCCC)C(Br)(c1cccc(C(Br)Br)c1Br)P(=O)(OCCCC)OCCCC

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CYP3A4 P08684 1/20 0.33
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL517592 0.79 GAA (0.38) MEN1ALDH1A1LMNAKMT2ANPSR1
SCHEMBL2872953 0.74 GAA (0.37) MEN1ALDH1A1KMT2ACYP3A4GAA
SCHEMBL518474 0.66 CYP3A4 (0.38) CYP3A4GAA
SCHEMBL3716530 0.64 CYP1A2 (0.46) ALDH1A1LMNANPSR1
SCHEMBL13337684 0.62 CYP3A4 (0.44) MEN1KMT2ACYP3A4
SCHEMBL517977 0.61 CYP3A4 (0.33) CYP3A4GAA
SCHEMBL13337642 0.60 MEN1 (0.49) MEN1KMT2ACYP3A4
SCHEMBL11673962 0.59
SCHEMBL12562679 0.59 CYP3A4 (0.58) CYP3A4
SCHEMBL11585760 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010046899-A2 IMPROVED FLAME RETARDATION OF TEXTILES BY HALOGENATED ARYL PHOSPHONATES BROMINE COMPOUNDS LTD. (IL) 2010-04-29 WO disclosed