Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 4/20 | 0.35 |
| ▸ | SSTR2 | P30874 | 3/20 | 0.35 |
| ▸ | ACACB | O00763 | 4/20 | 0.34 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.33 |
| ▸ | JAK1 | P23458 | 2/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28777548 | 1.00 | AXL (0.35) | AXLSSTR2ACACBCSNK1EHRH3 | |
| SCHEMBL28777550 | 1.00 | AXL (0.35) | AXLSSTR2ACACBCSNK1EHRH3 | |
| SCHEMBL28777613 | 0.90 | ACACB (0.33) | AXLSSTR2ACACBCSNK1EHRH3 | |
| Zavolosotine SCHEMBL22976175 | 0.88 | SSTR2 (0.38) | SSTR2RET | |
| Zavolosotine SCHEMBL22976253 | 0.88 | SSTR2 (0.38) | SSTR2RET | |
| Zavolosotine SCHEMBL22976246 | 0.88 | SSTR2 (0.38) | SSTR2RET | |
| Zavolosotine SCHEMBL29720052 | 0.88 | SSTR2 (0.38) | SSTR2RET | |
| Zavolosotine SCHEMBL22976243 | 0.88 | SSTR2 (0.38) | SSTR2RET | |
| Zavolosotine SCHEMBL22976228 | 0.88 | SSTR2 (0.38) | SSTR2RET | |
| Zavolosotine SCHEMBL29720019 | 0.88 | SSTR2 (0.38) | SSTR2RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114585614-A | Non-peptide somatostatin type 5 receptor agonists and uses thereof | 克林提克斯医药股份有限公司 | 2022-06-03 | — | — | CN | disclosed |