Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 13/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GNRHR | P30968 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4148031 | 0.85 | CASR (0.40) | CASRNR1I2HPGDGNRHR | |
| SCHEMBL28777976 | 0.85 | CASR (0.68) | CASRNR1I2 | |
| SCHEMBL27730648 | 0.83 | CASR (0.46) | CASRNR1I2HPGDGNRHRCNR1 | |
| SCHEMBL13851706 | 0.77 | CASR (0.39) | CASRNR1I2 | |
| SCHEMBL4144975 | 0.74 | CASR (0.72) | CASRNR1I2 | |
| SCHEMBL27751206 | 0.73 | CASR (0.68) | CASRNR1I2 | |
| SCHEMBL4143340 | 0.72 | CASR (0.76) | CASRNR1I2 | |
| SCHEMBL28774588 | 0.71 | CASR (0.57) | CASRNR1I2 | |
| SCHEMBL27751132 | 0.71 | CASR (0.64) | CASRNR1I2 | |
| SCHEMBL4145492 | 0.70 | CASR (0.51) | CASRNR1I2GNRHRCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101360498-A | Calcilytic compounds | SMITHKLINE BEECHAM CORP (US) | 2009-02-04 | — | — | CN | disclosed |