⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28777997 | 0.89 | — | — | |
| SCHEMBL28593761 | 0.81 | — | — | |
| SCHEMBL7183510 | 0.81 | — | — | |
| SCHEMBL23933132 | 0.79 | — | — | |
| SCHEMBL29749234 | 0.76 | KDM4E (0.37) | — | |
| SCHEMBL28777994 | 0.76 | — | — | |
| SCHEMBL26089009 | 0.71 | GAA (0.33) | — | |
| SCHEMBL1565127 | 0.70 | — | — | |
| SCHEMBL28637049 | 0.69 | — | — | |
| SCHEMBL23933140 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114685453-A | Heterocyclic prolinamide derivatives | 奥瑞恩眼科有限责任公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-109476637-B | Heterocyclic prolinamide derivatives | 奥瑞恩眼科有限责任公司 | 2022-02-01 | — | — | CN | disclosed |