Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | FAAH | O00519 | 2/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.58 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ADH1B | P00325 | 1/20 | 0.48 |
| ▸ | ADH1C | P00326 | 1/20 | 0.48 |
| ▸ | ADH1A | P07327 | 1/20 | 0.48 |
| ▸ | ADH4 | P08319 | 1/20 | 0.48 |
| ▸ | ADH7 | P40394 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Heptanal SCHEMBL29137696 | 0.81 | TSHR (0.89) | TSHRFAAHTRPV1EPHX1ALDH1A1 | |
| Tridecanal SCHEMBL27839282 | 0.81 | TSHR (0.89) | TSHRFAAHTRPV1EPHX1ALDH1A1 | |
| Decanal SCHEMBL2540 | 0.80 | TSHR (1.00) | TSHRFAAHTRPV1DNM1EPHX1 | |
| SCHEMBL120789 | 0.80 | TSHR (1.00) | TSHRFAAHTRPV1DNM1EPHX1 | |
| Undecanal SCHEMBL2684955 | 0.80 | TSHR (1.00) | TSHRFAAHTRPV1DNM1EPHX1 | |
| Heptanal SCHEMBL10533943 | 0.80 | TSHR (1.00) | TSHRFAAHTRPV1DNM1EPHX1 | |
| Decanal SCHEMBL7728978 | 0.80 | TSHR (1.00) | TSHRFAAHTRPV1DNM1EPHX1 | |
| Undecanal SCHEMBL22333 | 0.80 | TSHR (1.00) | TSHRFAAHTRPV1DNM1EPHX1 | |
| SCHEMBL9234870 | 0.80 | TSHR (1.00) | TSHRFAAHTRPV1DNM1EPHX1 | |
| Tridecanal SCHEMBL38928 | 0.80 | TSHR (1.00) | TSHRFAAHTRPV1DNM1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114621243-B | Sulfonamide derivative and application thereof | 上海拓界生物医药科技有限公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-114621243-A | Sulfonamide derivative and application thereof | 上海拓界生物医药科技有限公司 | 2022-06-14 | — | — | CN | disclosed |