Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 6/20 | 0.60 |
| ▸ | FAAH | O00519 | 7/20 | 0.48 |
| ▸ | CES1 | P23141 | 5/20 | 0.48 |
| ▸ | CES2 | O00748 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.47 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7024064 | 0.92 | FUCA1 (0.47) | EPHX1FAAHCES1CES2MEN1 | |
| Pivalate SCHEMBL5573578 | 0.86 | EPHX1 (0.62) | EPHX1MEN1KMT2AHSD17B10S1PR1 | |
| Bicarbonate SCHEMBL28237746 | 0.85 | EPHX1 (0.75) | EPHX1MEN1KMT2AHSD17B10S1PR1 | |
| Bicarbonate SCHEMBL28186030 | 0.85 | EPHX1 (0.75) | EPHX1MEN1KMT2AHSD17B10S1PR1 | |
| Bicarbonate SCHEMBL28186035 | 0.85 | EPHX1 (0.75) | EPHX1MEN1KMT2AHSD17B10S1PR1 | |
| Bicarbonate SCHEMBL28237747 | 0.85 | EPHX1 (0.75) | EPHX1MEN1KMT2AHSD17B10S1PR1 | |
| Bicarbonate SCHEMBL28186798 | 0.85 | EPHX1 (0.75) | EPHX1MEN1KMT2AHSD17B10S1PR1 | |
| Bicarbonate SCHEMBL28549811 | 0.85 | EPHX1 (0.75) | EPHX1MEN1KMT2AHSD17B10S1PR1 | |
| Bicarbonate SCHEMBL5430860 | 0.85 | EPHX1 (0.75) | EPHX1MEN1KMT2AHSD17B10S1PR1 | |
| Bicarbonate SCHEMBL28549810 | 0.85 | EPHX1 (0.75) | EPHX1MEN1KMT2AHSD17B10S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114621243-A | Sulfonamide derivative and application thereof | 上海拓界生物医药科技有限公司 | 2022-06-14 | — | — | CN | disclosed |