Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 12/20 | 0.81 |
| ▸ | CYSLTR2 | Q9NS75 | 11/20 | 0.80 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.80 |
| ▸ | MEN1 | O00255 | 1/20 | 0.80 |
| ▸ | RECQL | P46063 | 1/20 | 0.80 |
| ▸ | BLM | P54132 | 1/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.80 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.80 |
| ▸ | EGFR | P00533 | 1/20 | 0.80 |
| ▸ | ESR1 | P03372 | 1/20 | 0.80 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.80 |
| ▸ | FYN | P06241 | 1/20 | 0.80 |
| ▸ | PGR | P06401 | 1/20 | 0.80 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.80 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.80 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.80 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.80 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.80 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.80 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1535570 | 1.00 | CYSLTR1 (0.81) | CYSLTR1CYSLTR2CYP2C8MEN1RECQL | |
| SCHEMBL7405767 | 1.00 | CYSLTR1 (0.81) | CYSLTR1CYSLTR2CYP2C8MEN1RECQL | |
| SCHEMBL13452971 | 0.92 | CYSLTR1 (0.81) | CYSLTR1CYSLTR2CYP2C8MEN1RECQL | |
| SCHEMBL21888230 | 0.91 | CYSLTR1 (0.82) | CYSLTR1CYSLTR2CYP2C8MEN1RECQL | |
| SCHEMBL21888231 | 0.91 | CYSLTR1 (0.82) | CYSLTR1CYSLTR2CYP2C8MEN1RECQL | |
| SCHEMBL13941307 | 0.91 | CYSLTR1 (0.84) | CYSLTR1CYSLTR2CYP2C8MEN1RECQL | |
| SCHEMBL538484 | 0.90 | CYSLTR1 (0.82) | CYSLTR1CYSLTR2CYP2C8MEN1RECQL | |
| SCHEMBL537796 | 0.90 | CYSLTR1 (0.82) | CYSLTR1CYSLTR2CYP2C8MEN1RECQL | |
| SCHEMBL8761836 | 0.90 | CYSLTR1 (0.82) | CYSLTR1CYSLTR2CYP2C8MEN1RECQL | |
| SCHEMBL30719989 | 0.90 | CYSLTR1 (0.82) | CYSLTR1CYSLTR2CYP2C8MEN1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142508-A2 | PROCESS FOR THE PREPARATION OF SODIUM SALT OF L-(((L(R)-(3-(2-(7-CHLORO-2- QUINOLINYL)-ETHENYL)PHENYL)-3-(2-(L-HYDROXY-L- METHYLETHYL)PHENYL)PROPYL)SULFANYL)METHYL)CYCLOPROPANEACETIC ACID | Zaklady Farmaceutyczne "Polpharma" S.A. (PL) | 2010-01-13 | — | — | EP | disclosed |
| WO-2008136693-A3 | PROCESS FOR THE PREPARATION OF SODIUM SALT OF L-(((L(R)-(3-(2-(7-CHLORO-2- QUINOLINYL)-ETHENYL)PHENYL)-3-(2-(L-HYDROXY-L- METHYLETHYL)PHENYL)PROPYL)SULFANYL)METHYL)CYCLOPROPANEACETIC ACID | ZAKLADY FARM POLPHARMA SA (PL) | 2008-12-31 | — | — | WO | disclosed |
| WO-2008136693-A2 | PROCESS FOR THE PREPARATION OF SODIUM SALT OF L-(((L(R)-(3-(2-(7-CHLORO-2- QUINOLINYL)-ETHENYL)PHENYL)-3-(2-(L-HYDROXY-L- METHYLETHYL)PHENYL)PROPYL)SULFANYL)METHYL)CYCLOPROPANEACETIC ACID | ZAKLADY FARMACEUTYCZNE POLPHARMA SA (PL) | 2008-11-13 | — | — | WO | disclosed |