Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GLS | O94925 | 1/20 | 0.41 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | FPR3 | P25089 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28779682 | 1.00 | USP30 (0.48) | USP30MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL28779700 | 0.96 | EPHX1 (0.48) | USP30MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL28779703 | 0.96 | EPHX1 (0.48) | USP30MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL2892910 | 0.96 | USP30 (0.49) | USP30MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL29042867 | 0.92 | EPHX1 (0.48) | USP30MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL29042882 | 0.92 | EPHX1 (0.48) | USP30MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL29042866 | 0.92 | EPHX1 (0.48) | USP30MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL28779716 | 0.92 | USP30 (0.52) | USP30MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL6128815 | 0.92 | USP30 (0.52) | USP30MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL2729153 | 0.92 | USP30 (0.52) | USP30MEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114717211-B | Imine reductase mutant M5 and application thereof in synthesis of nitrogen heterocycle chiral amine | 江苏集萃分子工程研究院有限公司 | 2023-06-02 | — | — | CN | disclosed |
| CN-114717211-A | Imine reductase mutant M5 and application thereof in synthesis of azacyclo chiral amine | 江苏集萃分子工程研究院有限公司 | 2022-07-08 | — | — | CN | disclosed |