Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.62 |
| ▸ | STS | P08842 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | JAK1 | P23458 | 1/20 | 0.50 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.50 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 3/20 | 0.49 |
| ▸ | BCHE | P06276 | 2/20 | 0.49 |
| ▸ | FABP6 | P51161 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22222650 | 1.00 | USP30 (0.62) | USP30STSJAK2JAK1GPR119 | |
| SCHEMBL28779720 | 0.97 | USP30 (0.58) | USP30STSJAK2JAK1GPR119 | |
| SCHEMBL28779718 | 0.97 | USP30 (0.58) | USP30STSJAK2JAK1GPR119 | |
| SCHEMBL29043109 | 0.93 | USP30 (0.56) | USP30STSJAK2JAK1GPR119 | |
| SCHEMBL696779 | 0.93 | USP30 (0.56) | USP30STSJAK2JAK1GPR119 | |
| SCHEMBL696778 | 0.93 | USP30 (0.56) | USP30STSJAK2JAK1GPR119 | |
| SCHEMBL20267975 | 0.91 | STS (0.55) | USP30STSJAK2JAK1GPR119 | |
| SCHEMBL4171022 | 0.91 | STS (0.55) | USP30STSJAK2JAK1GPR119 | |
| SCHEMBL13434283 | 0.89 | HTT (0.51) | USP30STSBCHEACHE | |
| SCHEMBL17605512 | 0.89 | USP30 (0.50) | USP30GPR119BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115896050-B | 7 Alpha-hydroxysteroid dehydrogenase terminal modification combining point mutation and efficient synthesis of ursodeoxycholic acid intermediate | 江南大学 | 2025-06-24 | — | — | CN | disclosed |
| CN-114717211-B | Imine reductase mutant M5 and application thereof in synthesis of nitrogen heterocycle chiral amine | 江苏集萃分子工程研究院有限公司 | 2023-06-02 | — | — | CN | disclosed |
| CN-115896050-A | End transformation combined point mutation of 7 alpha-hydroxysteroid dehydrogenase and efficient synthesis of ursodeoxycholic acid intermediate | 江南大学 | 2023-04-04 | — | — | CN | disclosed |
| CN-114717211-A | Imine reductase mutant M5 and application thereof in synthesis of azacyclo chiral amine | 江苏集萃分子工程研究院有限公司 | 2022-07-08 | — | — | CN | disclosed |