SCHEMBL28779999

SCHEMBL28779999

Cc1cc2c(C(=O)O)cc(C)c(C)c2c(C)c1C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.40
HPGD P15428 2/20 0.40
HSD17B10 Q99714 2/20 0.40
GAA P10253 1/20 0.40
LDHA P00338 1/20 0.39
LDHB P07195 1/20 0.39
NOTUM Q6P988 3/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ALDH1A1 P00352 3/20 0.36
HMGB1 P09429 1/20 0.35
CXCL12 P48061 1/20 0.35
GABRP O00591 1/20 0.35
GABRD O14764 1/20 0.35
GABRA1 P14867 1/20 0.35
GABRB1 P18505 1/20 0.35
GABRG2 P18507 1/20 0.35
GABRB3 P28472 1/20 0.35
GABRA5 P31644 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27782294 0.82 MCL1 (0.43) KDM4EHPGDHSD17B10GAANOTUM
SCHEMBL29769767 0.76 KDM4E (0.48) KDM4EHPGDHSD17B10GAALDHA
SCHEMBL625521 0.76 KDM4E (0.48) KDM4EHPGDHSD17B10GAALDHA
SCHEMBL6916008 0.74 KDM4E (0.47) KDM4EHPGDHSD17B10GAALDHA
SCHEMBL6908680 0.74 KDM4E (0.47) KDM4EHPGDHSD17B10GAALDHA
SCHEMBL6913078 0.74 KDM4E (0.47) KDM4EHPGDHSD17B10GAALDHA
SCHEMBL6913400 0.74 KDM4E (0.47) KDM4EHPGDHSD17B10GAALDHA
SCHEMBL6915834 0.74 KDM4E (0.47) KDM4EHPGDHSD17B10GAALDHA
SCHEMBL6914572 0.74 KDM4E (0.47) KDM4EHPGDHSD17B10GAALDHA
Phosphine SCHEMBL28160666 0.74 KDM4E (0.47) KDM4EHPGDHSD17B10GAALDHA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101560272-B Olefinic polymerization catalyst, preparation method and polymerization method YINGKOU XIANGYANG CATALYST CO LTD 2011-04-13 CN disclosed
CN-101560273-B Olefinic polymerization catalyst, preparation method and polymerization method YINGKOU XIANGYANG CATALYST CO LTD 2011-03-23 CN disclosed
CN-101560272-A Olefinic polymerization catalyst, preparation method and polymerization method YINGKOU XIANGYANG CATALYST CO (CN) 2009-10-21 CN disclosed
CN-101560273-A Olefinic polymerization catalyst, preparation method and polymerization method YINGKOU XIANGYANG CATALYST CO (CN) 2009-10-21 CN disclosed