Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27772611 | 0.90 | HDAC1 (0.32) | HDAC1 | |
| SCHEMBL27772816 | 0.89 | HDAC1 (0.32) | HDAC1 | |
| SCHEMBL27794146 | 0.89 | PPARG (0.36) | HDAC1 | |
| SCHEMBL27794135 | 0.87 | TLR8 (0.34) | HDAC1 | |
| SCHEMBL962196 | 0.87 | CXCR2 (0.36) | IRAK4FFAR4NPY5RHDAC1TBXA2R | |
| SCHEMBL962198 | 0.87 | CXCR2 (0.36) | IRAK4FFAR4NPY5RHDAC1TBXA2R | |
| SCHEMBL27772597 | 0.85 | HDAC1 (0.32) | HDAC1 | |
| SCHEMBL27772683 | 0.85 | PPARG (0.36) | HDAC1 | |
| SCHEMBL965770 | 0.84 | PPARG (0.38) | IRAK4FFAR4TBXA2R | |
| SCHEMBL965767 | 0.84 | PPARG (0.38) | IRAK4FFAR4TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101646653-A | Fused ring compounds as partial agonists of ppar-gamma | TAKEDA PHARMACEUTICAL JP | 2010-02-10 | — | — | CN | disclosed |