Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2817833 | 0.89 | MEN1 (0.48) | MEN1KMT2AMAPTPOLBNPC1 | |
| SCHEMBL27775928 | 0.81 | MAPT (0.53) | MEN1KMT2AMAPTPOLBTP53 | |
| SCHEMBL28785584 | 0.79 | MEN1 (0.50) | MEN1KMT2AMAPTPOLBNPC1 | |
| SCHEMBL27797361 | 0.79 | MEN1 (0.50) | MEN1KMT2AMAPTPOLBTP53 | |
| SCHEMBL28785517 | 0.78 | MEN1 (0.55) | MEN1KMT2AMAPTPOLBTP53 | |
| SCHEMBL27797876 | 0.78 | MAPT (0.49) | MEN1KMT2AMAPTPOLBTP53 | |
| SCHEMBL27776356 | 0.78 | MAPT (0.48) | MEN1KMT2AMAPTPOLBTP53 | |
| SCHEMBL27796778 | 0.78 | AURKB (0.60) | MEN1KMT2AMAPTPOLBNPC1 | |
| SCHEMBL28782773 | 0.78 | KMT2A (0.48) | MEN1KMT2AMAPTPOLBNPC1 | |
| SCHEMBL27775767 | 0.77 | MEN1 (0.46) | MEN1KMT2AMAPTPOLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679215-A | New benzamide derivatives as the follicle stimulating hormone conditioning agent | ADDEX PHARMA SA | 2010-03-24 | — | — | CN | disclosed |