Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 6/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29712646 | 1.00 | GRM5 (0.81) | GRM5ALDH1A1NPSR1MAPTSMN1; SMN2 | |
| SCHEMBL29712712 | 0.95 | GRM5 (0.81) | GRM5ALDH1A1NPSR1MAPTSMN1; SMN2 | |
| SCHEMBL28782791 | 0.95 | GRM5 (0.81) | GRM5ALDH1A1NPSR1MAPTSMN1; SMN2 | |
| SCHEMBL29712639 | 0.90 | GRM5 (0.66) | GRM5ALDH1A1NPSR1MAPTSMN1; SMN2 | |
| SCHEMBL28330183 | 0.90 | GRM5 (0.66) | GRM5ALDH1A1NPSR1MAPTSMN1; SMN2 | |
| SCHEMBL1347180 | 0.90 | GRM5 (1.00) | GRM5SMN1; SMN2HTR1AHTR2AHTR7 | |
| Hydrochloric Acid SCHEMBL1346685 | 0.89 | GRM5 (0.98) | GRM5SMN1; SMN2HTR1AHTR2AHTR7 | |
| SCHEMBL28782799 | 0.86 | GRM5 (0.81) | GRM5ALDH1A1NPSR1SMN1; SMN2HTT | |
| SCHEMBL29712672 | 0.86 | GRM5 (0.81) | GRM5ALDH1A1NPSR1SMN1; SMN2HTT | |
| SCHEMBL29712653 | 0.86 | GRM5 (0.62) | GRM5ALDH1A1NPSR1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110467572-B | Synthetic method of 3-sulfonyl quinoline derivative | 温州大学 | 2022-07-08 | — | — | CN | disclosed |