Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 6/20 | 0.54 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29712654 | 1.00 | GRM5 (0.54) | GRM5NR1H2NR1H3KMT2AAURKA | |
| SCHEMBL8159365 | 0.88 | GRM5 (0.67) | GRM5 | |
| SCHEMBL29712634 | 0.84 | GRM5 (0.52) | GRM5NR1H2NR1H3KMT2AAURKA | |
| SCHEMBL28782785 | 0.84 | GRM5 (0.52) | GRM5NR1H2NR1H3KMT2AAURKA | |
| SCHEMBL12131537 | 0.84 | GRM5 (0.59) | GRM5NR1H2NR1H3AURKA | |
| SCHEMBL8159370 | 0.81 | GRM5 (0.56) | GRM5NR1H2NR1H3 | |
| SCHEMBL1125291 | 0.81 | NR1H2 (0.57) | GRM5NR1H2NR1H3 | |
| SCHEMBL8151175 | 0.80 | GRM5 (0.61) | GRM5NR1H2NR1H3 | |
| SCHEMBL1346905 | 0.79 | GRM5 (0.54) | GRM5NR1H2NR1H3 | |
| SCHEMBL29712639 | 0.79 | GRM5 (0.66) | GRM5AURKAKDM4EPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110467572-B | Synthetic method of 3-sulfonyl quinoline derivative | 温州大学 | 2022-07-08 | — | — | CN | disclosed |