Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15954532 | 0.81 | MAPT (0.56) | MAPTNPC1RAB9ANFKB1MAPK1 | |
| SCHEMBL2779294 | 0.81 | NPC1 (0.58) | MAPTNPC1RAB9ANFKB1MAPK1 | |
| SCHEMBL30113078 | 0.81 | MAPT (0.58) | MAPTNPC1RAB9ANFKB1MAPK1 | |
| SCHEMBL29153613 | 0.81 | MAPT (0.58) | MAPTNPC1RAB9ANFKB1MAPK1 | |
| SCHEMBL15954728 | 0.79 | MAPT (0.55) | MAPTNPC1RAB9ANFKB1MAPK1 | |
| SCHEMBL15954408 | 0.79 | MAPT (0.53) | MAPTNPC1RAB9ANFKB1MAPK1 | |
| Hydrochloric Acid SCHEMBL7880082 | 0.78 | MAPT (0.55) | MAPTNPC1RAB9ANFKB1MAPK1 | |
| SCHEMBL29241859 | 0.78 | MAPT (0.68) | MAPTNPC1RAB9ANFKB1MAPK1 | |
| SCHEMBL7158528 | 0.78 | MAPT (0.64) | MAPTNPC1RAB9ANFKB1MAPK1 | |
| SCHEMBL6799629 | 0.77 | MAPT (0.56) | MAPTNPC1RAB9ANFKB1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101778832-A | Oxopyrazine derivative and weedicide | KUMIAI CHEMICAL INDUSTRY CO | 2010-07-14 | — | — | CN | disclosed |