Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 4/20 | 0.32 |
| ▸ | CA1 | P00915 | 4/20 | 0.32 |
| ▸ | CA2 | P00918 | 4/20 | 0.32 |
| ▸ | CA9 | Q16790 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Peroxide SCHEMBL28342534 | 0.88 | TSHR (0.56) | TSHRHCAR2SMN1; SMN2GAAALDH1A1 | |
| Bicarbonate SCHEMBL6046311 | 0.85 | TSHR (0.53) | TSHRHCAR2SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL113233 | 0.85 | — | — | |
| SCHEMBL36670 | 0.85 | TSHR (0.59) | TSHRHCAR2ALDH1A1PDCD1CD274 | |
| Ammonia Solution, Strong SCHEMBL28066768 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL30675666 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL15092480 | 0.82 | TSHR (0.56) | TSHRHCAR2ALDH1A1PDCD1CD274 | |
| SCHEMBL6729295 | 0.82 | TSHR (0.56) | TSHRHCAR2ALDH1A1PDCD1CD274 | |
| SCHEMBL6726188 | 0.82 | TSHR (0.56) | TSHRHCAR2ALDH1A1PDCD1CD274 | |
| Ammonia Solution, Strong SCHEMBL16191762 | 0.82 | TSHR (0.56) | TSHRHCAR2ALDH1A1PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101781333-B | Adefovir dipivoxil crystal form and preparation method thereof | ZHEJIANG CHARIOTEER PHARMACEUTICAL CO LTD | 2013-06-05 | — | — | CN | disclosed |
| CN-101781333-A | Adefovir dipivoxil crystal form and preparation method thereof | ZHEJIANG CHARIOTEER PHARMACEUT | 2010-07-21 | — | — | CN | disclosed |