Acetic Acid

Acetic Acid

SCHEMBL28784356

CC(=O)O.CC(=O)O.CC(=O)O.NCCN(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 1/20 0.56
PRMT6 Q96LA8 1/20 0.56
PRMT8 Q9NR22 1/20 0.56
HDAC3 O15379 2/20 0.49
HDAC1 Q13547 2/20 0.49
HDAC2 Q92769 2/20 0.49
HDAC8 Q9BY41 2/20 0.49
NCOR2 Q9Y618 2/20 0.49
RORC P51449 1/20 0.47
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
CA12 O43570 1/20 0.46
CA9 Q16790 1/20 0.46
HTT P42858 1/20 0.45
DPP7 Q9UHL4 1/20 0.44
LMNA P02545 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
AOC3 Q16853 1/20 0.44
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL8440715 1.00 CARM1 (0.56) CARM1PRMT6PRMT8HDAC3HDAC1
Acetic Acid SCHEMBL28010133 1.00 CARM1 (0.56) CARM1PRMT6PRMT8HDAC3HDAC1
Acetic Acid SCHEMBL2252047 1.00 CARM1 (0.56) CARM1PRMT6PRMT8HDAC3HDAC1
Methyl Alcohol SCHEMBL28787466 0.90 CARM1 (0.62) CARM1PRMT6PRMT8HDAC3HDAC1
SCHEMBL21755 0.88 CARM1 (0.63) CARM1PRMT6PRMT8HDAC3HDAC1
SCHEMBL17763505 0.86 CARM1 (0.50) CARM1PRMT6PRMT8HDAC3HDAC1
Hydrochloric Acid SCHEMBL27797329 0.86 CARM1 (0.61) CARM1PRMT6PRMT8HDAC3HDAC1
Hydrochloric Acid SCHEMBL11047138 0.86 CARM1 (0.61) CARM1PRMT6PRMT8HDAC3HDAC1
Sulfuric Acid SCHEMBL28866057 0.85 CARM1 (0.52) CARM1PRMT6PRMT8HDAC3HDAC1
Phosphoric Acid SCHEMBL28953116 0.85 CARM1 (0.52) CARM1PRMT6PRMT8HDAC3HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101781317-B Method for preparing cephapirin benzathine GUANGZHOU BAIYUNSHAN PHARMACEUTICAL FACTORY GUANGZHOU BAIYUNSHAN PHARMACEUTICAL CO LTD 2012-03-28 CN disclosed
CN-101781317-A Method for preparing cephapirin benzathine GUANGZHOU BAIYUNSHAN PHARMACEU 2010-07-21 CN disclosed