Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MGAM | O43451 | 1/20 | 0.52 |
| ▸ | SI | P14410 | 1/20 | 0.52 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27867676 | 0.82 | MGAM (0.45) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL27882890 | 0.82 | MGAM (0.41) | GAAMGAMSIMGAM2EPHX2 | |
| SCHEMBL21818702 | 0.81 | GAA (0.52) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL20743953 | 0.81 | GAA (0.52) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL21818703 | 0.81 | GAA (0.52) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL28396393 | 0.81 | GAA (0.52) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL28728541 | 0.75 | GAA (0.45) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL6160692 | 0.74 | GAA (0.44) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL12953539 | 0.74 | EPHX2 (0.54) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL6160688 | 0.74 | GAA (0.44) | GAAMGAMSIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101605798-A | Imidazothiazole derivative | DAIICHI SANKYO CO LTD (JP) | 2009-12-16 | — | — | CN | disclosed |