Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 4/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.40 |
| ▸ | DHODH | Q02127 | 7/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27810966 | 0.93 | MEN1 (0.40) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL28784609 | 0.88 | MEN1 (0.42) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL3131577 | 0.85 | KMT2A (0.47) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL28784611 | 0.84 | ABL1 (0.39) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL27810967 | 0.82 | MEN1 (0.40) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL3131413 | 0.81 | MEN1 (0.40) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL3131940 | 0.81 | DHODH (0.43) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL3132683 | 0.79 | DHODH (0.41) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL3131583 | 0.79 | MEN1 (0.39) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL3128663 | 0.78 | MEN1 (0.43) | KMT2AALDH1A1MEN1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101801964-A | Heteroaryl substituted thiazoles and their use as antiviral agents | ACHILLION PHARMACEUTICALS INC | 2010-08-11 | — | — | CN | claimed |