Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 16/20 | 1.00 |
| ▸ | ROCK2 | O75116 | 10/20 | 1.00 |
| ▸ | PRKD3 | O94806 | 8/20 | 1.00 |
| ▸ | PRKCG | P05129 | 8/20 | 1.00 |
| ▸ | PRKCZ | Q05513 | 8/20 | 1.00 |
| ▸ | PRKCB | P05771 | 7/20 | 1.00 |
| ▸ | PRKCA | P17252 | 7/20 | 1.00 |
| ▸ | PRKCH | P24723 | 7/20 | 1.00 |
| ▸ | PRKCI | P41743 | 7/20 | 1.00 |
| ▸ | PRKCE | Q02156 | 7/20 | 1.00 |
| ▸ | PRKCD | Q05655 | 7/20 | 1.00 |
| ▸ | PRKD1 | Q15139 | 7/20 | 1.00 |
| ▸ | EGFR | P00533 | 7/20 | 0.82 |
| ▸ | PRKACA | P17612 | 7/20 | 0.82 |
| ▸ | PRKACG | P22612 | 6/20 | 0.82 |
| ▸ | PRKACB | P22694 | 6/20 | 0.82 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.79 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.79 |
| ▸ | KDR | P35968 | 3/20 | 0.79 |
| ▸ | MEN1 | O00255 | 2/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22765431 | 1.00 | PRKCQ (1.00) | PRKCQROCK2PRKD3PRKCGPRKCZ | |
| SCHEMBL30207128 | 1.00 | PRKCQ (1.00) | PRKCQROCK2PRKD3PRKCGPRKCZ | |
| SCHEMBL23259551 | 0.92 | PRKCQ (0.84) | PRKCQROCK2PRKD3PRKCGPRKCZ | |
| SCHEMBL20841734 | 0.91 | PRKCQ (1.00) | PRKCQROCK2PRKD3PRKCGPRKCZ | |
| SCHEMBL22765238 | 0.91 | PRKCQ (1.00) | PRKCQROCK2PRKD3PRKCGPRKCZ | |
| SCHEMBL12570343 | 0.91 | PRKCQ (1.00) | PRKCQROCK2PRKD3PRKCGPRKCZ | |
| SCHEMBL12570346 | 0.91 | PRKCQ (1.00) | PRKCQROCK2PRKD3PRKCGPRKCZ | |
| SCHEMBL13169904 | 0.90 | PRKCQ (0.82) | PRKCQROCK2PRKD3PRKCGPRKCZ | |
| SCHEMBL10108144 | 0.89 | PRKCQ (0.87) | PRKCQROCK2PRKD3PRKCGPRKCZ | |
| SCHEMBL2463656 | 0.89 | PRKCQ (0.87) | PRKCQROCK2PRKD3PRKCGPRKCZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101703509-A | Staurosporine derivatives as inhibitors of FLT3 receptor tyrosine kinase activity | NOVARTIS AG | 2010-05-12 | — | — | CN | disclosed |