Juarezic Acid

Juarezic Acid

SCHEMBL2878619

C=C(C)C(=O)O.C=CC(=O)OCCCC.O=C(O)C=CC=Cc1ccccc1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.49
TSHR P16473 1/20 0.49
TDP1 Q9NUW8 1/20 0.47
KDM4E B2RXH2 2/20 0.44
HCAR2 Q8TDS4 3/20 0.44
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
APP P05067 2/20 0.40
THRB P10828 1/20 0.40
AKR1B10 O60218 2/20 0.39
AKR1B1 P15121 2/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
ATM Q13315 1/20 0.38
BCHE P06276 2/20 0.38
ACHE P22303 1/20 0.38
ALDH1A1 P00352 1/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Juarezic Acid SCHEMBL1627203 0.94 TSHR (0.55) HPGDTSHRTDP1KDM4EHCAR2
Juarezic Acid SCHEMBL8887961 0.94 TSHR (0.55) HPGDTSHRTDP1KDM4EHCAR2
Juarezic Acid SCHEMBL11394473 0.92 TDP1 (0.49) HPGDTSHRTDP1KDM4EHCAR2
Juarezic Acid SCHEMBL5383036 0.90 HCAR2 (0.51) HPGDTSHRTDP1KDM4EHCAR2
Juarezic Acid SCHEMBL29001952 0.89 TDP1 (0.47) HPGDTSHRTDP1KDM4EHCAR2
SCHEMBL30023403 0.88 TSHR (0.63) HPGDTSHRTDP1KDM4EHCAR2
Juarezic Acid SCHEMBL8680144 0.88 HPGD (0.48) HPGDTSHRTDP1KDM4EHCAR2
Styrene SCHEMBL3915927 0.85 TSHR (0.55) HPGDTSHRTDP1KDM4EHCAR2
Styrene SCHEMBL1563744 0.85 TSHR (0.58) HPGDTSHRTDP1KDM4EHCAR2
SCHEMBL3111140 0.83 TSHR (0.56) HPGDTSHRTDP1KDM4EHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2568021-B1 Ink Composition HEWLETT PACKARD DEVELOPMENT CO (US) 2019-05-08 EP disclosed
US-8454737-B2 Ink composition HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2013-06-04 US disclosed
US-20130065031-A1 INK COMPOSITION HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2013-03-14 US disclosed
EP-2568021-A2 Ink Composition Hewlett-Packard Development Company, L.P. (US) 2013-03-13 EP disclosed
EP-1965898-B1 PIGMENTED INK-JET INKS WITH IMPROVED IMAGE QUALITY ON GLOSSY MEDIA HEWLETT PACKARD DEVELOPMENT CO (US) 2010-10-20 EP disclosed
US-7655707-B2 Pigmented ink-jet inks with improved image quality on glossy media HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2010-02-02 US disclosed
EP-1965898-A2 PIGMENTED INK-JET INKS WITH IMPROVED IMAGE QUALITY ON GLOSSY MEDIA Hewlett-Packard Development Company, L.P. (US) 2008-09-10 EP disclosed
WO-2007094882-A2 PIGMENTED INK-JET INKS WITH IMPROVED IMAGE QUALITY ON GLOSSY MEDIA HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2007-08-23 WO disclosed
US-20070129462-A1 Pigmented ink-jet inks with improved image quality on glossy media HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2007-06-07 US disclosed