Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 18/20 | 0.61 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.61 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.61 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.61 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12005462 | 1.00 | PIK3CD (0.61) | PIK3CDPIK3CGPIK3CAPIK3CBMAP4K4 | |
| Amg-319 SCHEMBL16799298 | 0.89 | PIK3CD (0.76) | PIK3CDPIK3CGPIK3CAPIK3CB | |
| Amg-319 SCHEMBL4185718 | 0.89 | PIK3CD (0.76) | PIK3CDPIK3CGPIK3CAPIK3CB | |
| Amg-319 SCHEMBL17240940 | 0.88 | PIK3CD (0.75) | PIK3CDPIK3CGPIK3CAPIK3CB | |
| SCHEMBL4171127 | 0.87 | PIK3CD (0.57) | PIK3CDPIK3CGPIK3CAPIK3CBMAP4K4 | |
| SCHEMBL27802785 | 0.87 | PIK3CD (0.57) | PIK3CDPIK3CGPIK3CAPIK3CBMAP4K4 | |
| SCHEMBL4174885 | 0.86 | PIK3CD (0.59) | PIK3CDPIK3CGPIK3CAPIK3CBMAP4K4 | |
| SCHEMBL4182647 | 0.86 | PIK3CD (0.59) | PIK3CDPIK3CGPIK3CAPIK3CBMAP4K4 | |
| SCHEMBL12005493 | 0.85 | PIK3CD (0.56) | PIK3CDPIK3CGPIK3CAPIK3CBMAP4K4 | |
| SCHEMBL10285587 | 0.84 | PIK3CD (0.59) | PIK3CDPIK3CGPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101715453-B | Heterocyclic compounds and their uses | AMGEN INC | 2012-06-27 | — | — | CN | disclosed |
| CN-101715453-A | Heterogeneous ring compound and application thereof | AMGEN INC | 2010-05-26 | — | — | CN | disclosed |