Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRA | P16234 | 14/20 | 0.75 |
| ▸ | ABL1 | P00519 | 12/20 | 0.75 |
| ▸ | BCR | P11274 | 6/20 | 0.75 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.75 |
| ▸ | EGFR | P00533 | 1/20 | 0.75 |
| ▸ | PRKCA | P17252 | 1/20 | 0.75 |
| ▸ | KIT | P10721 | 6/20 | 0.73 |
| ▸ | KDR | P35968 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27781979 | 0.92 | PDGFRA (0.81) | PDGFRAABL1BCRPDGFRBEGFR | |
| SCHEMBL27803518 | 0.89 | PDGFRA (0.75) | PDGFRAABL1BCRPDGFRBEGFR | |
| SCHEMBL27781981 | 0.89 | PDGFRA (0.64) | PDGFRAABL1BCRPDGFRBEGFR | |
| SCHEMBL27803465 | 0.89 | ABL1 (0.74) | PDGFRAABL1BCRPDGFRBEGFR | |
| SCHEMBL2004455 | 0.87 | PDGFRA (0.91) | PDGFRAABL1BCRPDGFRBEGFR | |
| SCHEMBL27803466 | 0.86 | ABL1 (0.68) | PDGFRAABL1BCRPDGFRBEGFR | |
| SCHEMBL27781978 | 0.86 | PDGFRA (0.73) | PDGFRAABL1BCRPDGFRBEGFR | |
| SCHEMBL9782 | 0.86 | PDGFRA (1.00) | PDGFRAABL1BCRPDGFRBEGFR | |
| SCHEMBL29498750 | 0.86 | PDGFRA (1.00) | PDGFRAABL1BCRPDGFRBEGFR | |
| SCHEMBL4801110 | 0.85 | ABL1 (0.84) | PDGFRAABL1BCRPDGFRBEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101720322-A | Compounds and compositions as c-kit and pdgfr kinase inhibitors | IRM LLC | 2010-06-02 | — | — | CN | claimed |
| CN-101720322-A | Compounds and compositions as c-kit and pdgfr kinase inhibitors | IRM LLC | 2010-06-02 | — | — | CN | disclosed |