Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 5/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 6/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2009405 | 1.00 | ABCB1 (0.53) | ABCB1IDO1KDM4ECYP3A4CYP2C19 | |
| SCHEMBL2008329 | 0.90 | ABCB1 (0.43) | ABCB1IDO1KDM4ECYP3A4CYP2C19 | |
| SCHEMBL3596079 | 0.90 | ABCB1 (0.43) | ABCB1IDO1KDM4ECYP3A4CYP2C19 | |
| SCHEMBL2881077 | 0.90 | ABCB1 (0.43) | ABCB1IDO1KDM4ECYP3A4CYP2C19 | |
| SCHEMBL2008331 | 0.90 | ABCB1 (0.43) | ABCB1IDO1KDM4ECYP3A4CYP2C19 | |
| SCHEMBL2873587 | 0.89 | ABCB1 (0.41) | ABCB1IDO1KDM4ECYP3A4CYP2C19 | |
| SCHEMBL2013593 | 0.89 | ABCB1 (0.41) | ABCB1IDO1KDM4ECYP3A4CYP2C19 | |
| SCHEMBL2007655 | 0.86 | ABCB1 (0.38) | ABCB1IDO1KDM4ECYP3A4CYP2C19 | |
| SCHEMBL2891745 | 0.86 | ABCB1 (0.38) | ABCB1IDO1KDM4ECYP3A4CYP2C19 | |
| SCHEMBL2875956 | 0.86 | ABCB1 (0.38) | ABCB1IDO1KDM4ECYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732929-B1 | TRICYCLIC BENZOPYRAN COMPOUND AS ANTI-ARRHYTHMIC AGENTS | NISSAN CHEMICAL IND LTD (JP) | 2010-10-20 | — | — | EP | disclosed |
| US-20100069374-A1 | Tricyclic benzopyrane compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-03-18 | — | — | US | disclosed |
| US-7652008-B2 | 2,2,7,9-tetramethyl-4-[(2-phenylethyl)amino]-3,4-dihydro-2H-pyrano[2,3-g]quinolin-3-ol; 3-hydroxy-2,2,9-trimethyl-4-[(2-phenylethyl)amino]-3,4-dihydro-2H-pyrano[2,3-g]quinolin-7-carbonitrile; have the prolongation effect on refractory period | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-01-26 | — | — | US | disclosed |
| US-20080004262-A1 | Tricyclic Benzopyrane Compound as Anti-Arrhythmic Agents | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2008-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069374-A1 | Tricyclic benzopyrane compound | CBR1, CBR3, CYP2C9 | ABCB1 647/4885IDO1 2850/4885KDM4E 3259/4885 |
| US-20080004262-A1 | Tricyclic Benzopyrane Compound as Anti-Arrhythmic Agents | CBR1, CBR3, SCN8A | ABCB1 580/4885IDO1 3364/4885KDM4E 3021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.