Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27610820 | 0.87 | DPP4 (0.59) | DPP4CYP2D6SRCLMNAMAPK1 | |
| SCHEMBL27974222 | 0.83 | DPP4 (0.45) | DPP4CYP2D6SRCLMNAMAPK1 | |
| SCHEMBL27603754 | 0.82 | HDAC1 (0.52) | DPP4LMNA | |
| SCHEMBL27865174 | 0.79 | KMT2A (0.56) | DPP4CYP2D6SRCLMNAMAPK1 | |
| SCHEMBL11390783 | 0.79 | BRD4 (0.53) | CYP2D6SRCLMNAMAPK1 | |
| SCHEMBL28837744 | 0.79 | DPP4 (0.41) | DPP4CYP2D6PKMSLC7A5 | |
| SCHEMBL6159580 | 0.78 | CYP2D6 (0.46) | CYP2D6SRCLMNAMAPK1PTGS1 | |
| SCHEMBL7710838 | 0.78 | DPP4 (0.52) | DPP4CYP2D6SRCLMNAADRA2A | |
| SCHEMBL9671856 | 0.78 | CYP2D6 (0.46) | CYP2D6SRCLMNAMAPK1PTGS1 | |
| SCHEMBL8219735 | 0.78 | DPP4 (0.52) | DPP4CYP2D6SRCLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102076342-A | Novel nitroso compounds as nitroxyl donors and methods of use thereof | CARDIOXYL PHARMACEUTICALS INC | 2011-05-25 | — | — | CN | disclosed |