Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.87 |
| ▸ | TP53 | P04637 | 1/20 | 0.87 |
| ▸ | BCHE | P06276 | 8/20 | 0.77 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | TSHR | P16473 | 2/20 | 0.73 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.73 |
| ▸ | NPY1R | P25929 | 1/20 | 0.73 |
| ▸ | NPY2R | P49146 | 1/20 | 0.73 |
| ▸ | USP2 | O75604 | 1/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29728192 | 1.00 | MAPT (0.87) | MAPTTP53BCHELMNATSHR | |
| SCHEMBL1900273 | 0.88 | BCHE (0.77) | MAPTTP53BCHELMNATSHR | |
| SCHEMBL29728204 | 0.87 | BCHE (1.00) | MAPTTP53BCHELMNATSHR | |
| SCHEMBL28787629 | 0.87 | BCHE (1.00) | MAPTTP53BCHELMNATSHR | |
| SCHEMBL28576916 | 0.87 | BCHE (1.00) | BCHE | |
| SCHEMBL29728188 | 0.86 | BCHE (0.78) | MAPTTP53BCHELMNATSHR | |
| SCHEMBL28944914 | 0.86 | BCHE (0.78) | MAPTTP53BCHELMNATSHR | |
| SCHEMBL1901750 | 0.86 | BCHE (0.75) | MAPTTP53BCHELMNATSHR | |
| SCHEMBL28787610 | 0.86 | BCHE (0.84) | MAPTTP53BCHE | |
| SCHEMBL29728214 | 0.86 | BCHE (0.84) | MAPTTP53BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109265451-B | Butyrylcholinesterase selective inhibitor and preparation method and application thereof | 中国药科大学 | 2022-07-15 | — | — | CN | disclosed |