Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.73 |
| ▸ | CHKA | P35790 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HBB | P68871 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbimide SCHEMBL28028271 | 0.91 | CHRM5 (0.80) | CHRM5CHKAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL189 | 0.85 | — | — | |
| SCHEMBL8664726 | 0.85 | CHRM5 (1.00) | CHRM5CHKAMAPTSMN1; SMN2KMT2A | |
| Formaldehyde SCHEMBL27435490 | 0.83 | CHRM5 (0.84) | CHRM5CHKAMAPTSMN1; SMN2KMT2A | |
| Phosphine SCHEMBL23270013 | 0.83 | CHRM5 (0.94) | CHRM5CHKAMAPTSMN1; SMN2KMT2A | |
| Bromide SCHEMBL393565 | 0.83 | CHRM5 (0.94) | CHRM5CHKAMAPTSMN1; SMN2KMT2A | |
| Bromide SCHEMBL393564 | 0.83 | CHRM5 (0.94) | CHRM5CHKAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL4405649 | 0.83 | CHRM5 (0.94) | CHRM5CHKAMAPTSMN1; SMN2KMT2A | |
| Bromide SCHEMBL1542160 | 0.83 | CHRM5 (0.94) | CHRM5CHKAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL2277093 | 0.83 | CHRM5 (0.94) | CHRM5CHKAMAPTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102089289-A | Novel heterocyclyl compounds for treatment of cardiovascular disease | HOFFMANN LA ROCHE | 2011-06-08 | — | — | CN | disclosed |