Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 13/20 | 0.84 |
| ▸ | HDAC3 | O15379 | 12/20 | 0.84 |
| ▸ | HDAC2 | Q92769 | 12/20 | 0.84 |
| ▸ | NCOR2 | Q9Y618 | 4/20 | 0.84 |
| ▸ | TACR1 | P25103 | 1/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.62 |
| ▸ | CTSL | P07711 | 1/20 | 0.62 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.58 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.58 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27839978 | 0.92 | HDAC1 (0.80) | HDAC1HDAC3HDAC2NCOR2TACR1 | |
| SCHEMBL27839974 | 0.92 | HDAC1 (0.80) | HDAC1HDAC3HDAC2NCOR2TACR1 | |
| SCHEMBL27820625 | 0.88 | HDAC1 (0.75) | HDAC1HDAC3HDAC2NCOR2TACR1 | |
| SCHEMBL27839976 | 0.87 | HDAC1 (0.70) | HDAC1HDAC3HDAC2NCOR2HDAC6 | |
| SCHEMBL28793104 | 0.85 | HDAC1 (0.70) | HDAC1HDAC3HDAC2NCOR2TACR1 | |
| SCHEMBL28793141 | 0.84 | HDAC1 (0.67) | HDAC1HDAC3HDAC2NCOR2TACR1 | |
| SCHEMBL27820632 | 0.83 | HDAC1 (0.67) | HDAC1HDAC3HDAC2NCOR2TACR1 | |
| SCHEMBL27820613 | 0.83 | HDAC1 (0.65) | HDAC1HDAC3HDAC2NCOR2TACR1 | |
| SCHEMBL3557636 | 0.80 | HDAC1 (0.62) | HDAC1HDAC3HDAC2NCOR2HDAC6 | |
| SCHEMBL9271917 | 0.79 | TACR1 (1.00) | HDAC1HDAC3HDAC2NCOR2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102180826-A | Histone deacetylase inhibitor containing alpha amino acid structure and application thereof | UNIV CHINA PHARMA | 2011-09-14 | — | — | CN | disclosed |