SCHEMBL28790146

SCHEMBL28790146

Cn1c2c(c3ccc(-n4ccc(OCc5cn6ccccc6n5)cc4=O)cc31)CCN(C(=O)O)C2

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 20/20 0.59
CYP3A4 P08684 3/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3477404 0.94 MCHR1 (0.66) MCHR1CYP3A4
SCHEMBL3476889 0.92 MCHR1 (0.54) MCHR1CYP3A4
SCHEMBL3475251 0.90 MCHR1 (0.71) MCHR1CYP3A4
Hydrochloric Acid SCHEMBL3476133 0.89 MCHR1 (0.70) MCHR1CYP3A4
SCHEMBL3476562 0.86 MCHR1 (0.64) MCHR1CYP3A4
SCHEMBL13025210 0.86 MCHR1 (0.58) MCHR1CYP3A4
SCHEMBL3476898 0.86 MCHR1 (0.60) MCHR1CYP3A4
SCHEMBL11425690 0.86 MCHR1 (0.71) MCHR1CYP3A4
SCHEMBL3477422 0.85 MCHR1 (0.80) MCHR1CYP3A4
Hydrochloric Acid SCHEMBL3477102 0.85 MCHR1 (0.70) MCHR1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101945872-B (1-azinone) -substituted pyridoindoles as mch antagonists ALBANY MOLECULAR RES INC 2014-07-23 CN disclosed
CN-101945872-A (1-azinone) -substituted pyridoindoles as mch antagonists ALBANY MOLECULAR RES INC 2011-01-12 CN disclosed