Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNIK | Q9UKE5 | 18/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3499686 | 0.88 | TNIK (0.65) | TNIKTP53MAPTLMNAPOLB | |
| SCHEMBL15663252 | 0.86 | TNIK (0.60) | TNIKTP53MAPTLMNAPOLB | |
| SCHEMBL3398128 | 0.84 | TNIK (0.77) | TNIKTP53MAPTLMNAPOLB | |
| SCHEMBL3394629 | 0.83 | TP53 (0.77) | TNIKTP53MAPTLMNAPOLB | |
| SCHEMBL2366931 | 0.82 | TNIK (0.67) | TNIKTP53MAPTLMNAPOLB | |
| SCHEMBL3435797 | 0.80 | TNIK (0.67) | TNIKTP53MAPTLMNAPOLB | |
| SCHEMBL3394949 | 0.80 | TNIK (0.64) | TNIKTP53MAPTLMNAPOLB | |
| SCHEMBL2367144 | 0.80 | TNIK (0.71) | TNIKTP53MAPTLMNAPOLB | |
| SCHEMBL2366979 | 0.80 | TNIK (0.85) | TNIKTP53MAPTLMNAPOLB | |
| SCHEMBL3396885 | 0.79 | TNIK (0.68) | TNIKTP53MAPTLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102227218-A | Tnik inhibitor and use thereof | TESSHI YAMADA | 2011-10-26 | — | — | CN | disclosed |