Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.50 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 4/20 | 0.38 |
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4818350 | 0.78 | PBRM1 (0.58) | PBRM1IL4I1HRH3MAOAMAOB | |
| SCHEMBL1512782 | 0.78 | PBRM1 (0.53) | PBRM1IL4I1HRH3MAOAMAOB | |
| SCHEMBL7605245 | 0.78 | PBRM1 (0.53) | PBRM1IL4I1HRH3MAOAMAOB | |
| SCHEMBL26703825 | 0.78 | PBRM1 (0.53) | PBRM1IL4I1HRH3MAOAMAOB | |
| SCHEMBL31660699 | 0.78 | PBRM1 (0.58) | PBRM1IL4I1HRH3MAOAMAOB | |
| SCHEMBL4812956 | 0.75 | PBRM1 (0.55) | PBRM1IL4I1HRH3MAOAMAOB | |
| SCHEMBL8688671 | 0.75 | PBRM1 (0.50) | PBRM1IL4I1HRH3MAOAMAOB | |
| SCHEMBL23397539 | 0.74 | PBRM1 (0.49) | PBRM1IL4I1HRH3MAOAMAOB | |
| SCHEMBL4815514 | 0.74 | PBRM1 (0.49) | PBRM1IL4I1HRH3MAOAMAOB | |
| SCHEMBL18618556 | 0.74 | PBRM1 (0.49) | PBRM1IL4I1HRH3MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102066328-A | Iminopyridine derivative and use thereof | TAKEDA PHARMACEUTICAL | 2011-05-18 | — | — | CN | disclosed |