Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 19/20 | 0.72 |
| ▸ | AURKA | O14965 | 17/20 | 0.72 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.67 |
| ▸ | CSF1R | P07333 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL665542 | 0.85 | RPS6KB1 (0.86) | RPS6KB1AURKAAURKBCSF1R | |
| SCHEMBL666838 | 0.84 | RPS6KB1 (1.00) | RPS6KB1AURKAAURKB | |
| SCHEMBL665132 | 0.80 | AURKA (1.00) | RPS6KB1AURKAAURKB | |
| SCHEMBL27830387 | 0.80 | RPS6KB1 (0.76) | RPS6KB1AURKAAURKB | |
| SCHEMBL666018 | 0.80 | AURKA (1.00) | RPS6KB1AURKAAURKB | |
| SCHEMBL27830109 | 0.77 | RPS6KB1 (0.75) | RPS6KB1AURKAAURKB | |
| SCHEMBL3472939 | 0.75 | CSF1R (1.00) | RPS6KB1AURKAAURKBCSF1R | |
| SCHEMBL29119483 | 0.75 | CSF1R (1.00) | RPS6KB1AURKAAURKBCSF1R | |
| SCHEMBL30672123 | 0.75 | CSF1R (1.00) | RPS6KB1AURKAAURKBCSF1R | |
| SCHEMBL667740 | 0.74 | RPS6KB1 (0.83) | RPS6KB1AURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102317269-A | Novel amino aza heterocyclic carboxamides | MERCK PATENT GMBH | 2012-01-11 | — | — | CN | disclosed |