Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 17/20 | 0.39 |
| ▸ | PRKDC | P78527 | 2/20 | 0.39 |
| ▸ | MTOR | P42345 | 7/20 | 0.38 |
| ▸ | ATR | Q13535 | 5/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.38 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.35 |
| ▸ | PI4KA | P42356 | 2/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29742725 | 1.00 | ATM (0.39) | ATMPRKDCMTORATRPIK3CB | |
| SCHEMBL29688283 | 0.90 | ATM (0.42) | ATMPRKDCMTORATRPIK3CB | |
| SCHEMBL23093827 | 0.90 | ATM (0.42) | ATMPRKDCMTORATRPIK3CB | |
| SCHEMBL29688027 | 0.87 | ATM (0.48) | ATMPRKDCMTORATRPIK3CB | |
| SCHEMBL23119186 | 0.87 | ATM (0.49) | ATMPRKDCMTORATRPIK3CB | |
| SCHEMBL23093840 | 0.87 | ATM (0.48) | ATMPRKDCMTORATRPIK3CB | |
| SCHEMBL23119299 | 0.87 | ATM (0.54) | ATMPRKDCMTORATRPIK3CB | |
| SCHEMBL23093830 | 0.87 | ATM (0.54) | ATMPRKDCMTORATRPIK3CB | |
| SCHEMBL23119298 | 0.87 | ATM (0.54) | ATMPRKDCMTORATRPIK3CB | |
| SCHEMBL23093862 | 0.86 | ATM (0.41) | ATMPRKDCMTORATRPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114787162-A | Substituted imidazoquinoxaline compounds and uses thereof | 上海瑛派药业有限公司 | 2022-07-22 | — | — | CN | claimed |
| CN-114787162-A | Substituted imidazoquinoxaline compounds and uses thereof | 上海瑛派药业有限公司 | 2022-07-22 | — | — | CN | disclosed |