Chromanone

Chromanone

SCHEMBL28794

O=C1CCOc2ccccc21

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 7/20 0.56
MAOA P21397 2/20 0.56
GRM5 P41594 4/20 0.56
PKM P14618 1/20 0.52
TSHR P16473 1/20 0.52
SMN1; SMN2 Q16637 3/20 0.50
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
ALDH1A1 P00352 1/20 0.50
HPGD P15428 1/20 0.50
NFKB1 P19838 1/20 0.50
NFKB2 Q00653 1/20 0.50
RELA Q04206 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
ITGB2 P05107 1/20 0.48
ICAM1 P05362 1/20 0.48
ITGAL P20701 1/20 0.48
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
NOTUM Q6P988 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chromanone SCHEMBL28205525 1.00 MAOB (0.56) MAOBMAOAGRM5PKMTSHR
Chromanone SCHEMBL29384996 1.00 MAOB (0.56) MAOBMAOAGRM5PKMTSHR
Chromanone SCHEMBL30017864 0.98 MAOB (0.55) MAOBMAOAGRM5PKMTSHR
Chromanone SCHEMBL27846233 0.98 MAOB (0.55) MAOBMAOAGRM5PKMTSHR
Chromanone SCHEMBL29349977 0.98 MAOB (0.55) MAOBMAOAGRM5PKMTSHR
Chromanone SCHEMBL28463260 0.98 MAOB (0.55) MAOBMAOAGRM5PKMTSHR
Chromanone SCHEMBL28719460 0.98 MAOB (0.55) MAOBMAOAGRM5PKMTSHR
Chromanone SCHEMBL7617916 0.98 MAOB (0.55) MAOBMAOAGRM5PKMTSHR
Chromanone SCHEMBL28145031 0.96 MAOB (0.53) MAOBMAOAGRM5PKMTSHR
Chromanone SCHEMBL29288344 0.94 MAOB (0.51) MAOBMAOAGRM5PKMTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4326 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137794-A1 LIGAND-DRUG CONJUGATE AND USE THEREOF SYSTIMMUNE INC (US) 2026-05-21 US claimed
EP-4678634-A1 ANDROGEN RECEPTOR MODULATORS AND USES THEREOF Haihe Biopharma Co., Ltd. (CN) 2026-01-14 EP claimed
EP-4527416-A1 LIGAND-DRUG CONJUGATE AND USE THEREOF SystImmune, Inc. (US) 2025-03-26 EP claimed
WO-2025043213-A2 THERAPEUTIC COMPOUNDS AND METHODS UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2025-02-27 WO claimed
CN-119504679-A Chromanone compound and application thereof in preventing and treating kiwi fruit bacterial canker 安徽农业大学 2025-02-25 CN claimed
CN-114007624-B Use of 3-oxo-sulfamoyloxy-7β -methyl-D-pro-6-oxaestra-1, 3,5 (10), 8 (9) -tetraen-17 a-one for the treatment of breast cancer 纳塔利娅·爱德华多夫娜·伊利娅索娃 2025-02-14 CN claimed
US-12213959-B2 Use of 3-O-sulfamoyloxy-7β-methyl-d-homo-6-oxaestra-1,3,5(10),8(9)-tetraen-17a-one to treat breast cancer ILIASOVA, NATALIA (RU) 2025-02-04 US claimed
CN-119371410-A Chromone spiro compound and preparation method and application thereof 中国药科大学 2025-01-28 CN claimed
WO-2023222019-A9 LIGAND-DRUG CONJUGATE AND USE THEREOF 成都百利多特生物药业有限责任公司 2024-11-14 WO claimed
CN-118908948-A Chromanone compound containing 1, 3-oxazole fragment and synthetic method and application thereof 重庆文理学院 2024-11-08 CN claimed
EP-0118685-A1 Propene derivatives and their use as plant growth inhibitors DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1984-09-19 EP claimed
EP-0117412-A1 Propene derivatives and their use as plant growth inhibitors DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1984-09-05 EP claimed
EP-0087858-A1 New chromanone compounds and pharmaceutical compositions containing them NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) 1983-09-07 EP claimed
EP-0004624-B1 CHROMANON DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS MEDICINES AND GROWTH-PROMOTING AGENTS BAYER AG (DE) 1982-02-24 EP claimed
EP-0037672-A2 Process for the preparation of chiral hydantoins, and a novel hydantoin produced by said process and a pharmaceutical composition containing it PFIZER INC. (US) 1981-10-14 EP claimed
US-4286098-A HYPOGLYCEMIC AGENTS, TREATMENT OF DIABETES COMPLICATIONS PFIZER INC. (US) 1981-08-25 US claimed
US-4256819-A MEROCYANINES EASTMAN KODAK COMPANY (US) 1981-03-17 US claimed
US-4214963-A Process for the preparation of substituted 4H-pyran-4-ones Garcia de Lama, Javier (ES) 1980-07-29 US claimed
EP-0004624-A2 Chromanon derivatives, process for their preparation, and their use as medicines and growth-promoting agents BAYER AG (DE) 1979-10-17 EP claimed
EP-0001428-A1 Insecticidal and acaricidal agents containing chroman derivatives, their preparation and their use, as well as chroman derivatives and their preparation BAYER AG (DE) 1979-04-18 EP claimed