Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 15/20 | 0.74 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ATP4A | P20648 | 1/20 | 0.45 |
| ▸ | ATP4B | P51164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19631418 | 1.00 | DHODH (0.74) | DHODHGSTO1LMNAALDH1A1KMT2A | |
| SCHEMBL20956575 | 0.87 | DHODH (0.67) | DHODHGSTO1KMT2AATP4AATP4B | |
| SCHEMBL20956573 | 0.87 | DHODH (0.67) | DHODHGSTO1KMT2AATP4AATP4B | |
| SCHEMBL29911563 | 0.85 | DHODH (1.00) | DHODHGSTO1ALDH1A1 | |
| SCHEMBL19631365 | 0.85 | DHODH (1.00) | DHODHGSTO1ALDH1A1 | |
| SCHEMBL20956565 | 0.85 | DHODH (1.00) | DHODHGSTO1ALDH1A1 | |
| SCHEMBL19631432 | 0.80 | DHODH (0.78) | DHODHGSTO1 | |
| SCHEMBL19631360 | 0.78 | DHODH (0.78) | DHODHALDH1A1 | |
| SCHEMBL19631361 | 0.78 | DHODH (0.78) | DHODHGSTO1 | |
| SCHEMBL25614262 | 0.78 | DHODH (0.53) | DHODHLMNAALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107375279-B | Use of novel thiazole derivatives for the treatment of inflammatory bowel disease | 华东理工大学 | 2022-11-01 | — | — | CN | disclosed |
| CN-107459496-B | Use of thiazole derivatives for treating viral infections | 华东理工大学 | 2022-07-19 | — | — | CN | disclosed |