Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | CASP1 | P29466 | 4/20 | 0.49 |
| ▸ | CASP7 | P55210 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30098131 | 1.00 | ASAH1 (0.55) | ASAH1ALDH1A1HSD17B10KDM4EMAPT | |
| SCHEMBL29795450 | 0.80 | ASAH1 (0.69) | ASAH1ALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL28794854 | 0.80 | ASAH1 (0.69) | ASAH1ALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL29795545 | 0.79 | ASAH1 (0.62) | ASAH1ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL24810609 | 0.79 | MEN1 (0.48) | ALDH1A1HSD17B10KDM4EMAPTCASP1 | |
| SCHEMBL29795635 | 0.77 | ASAH1 (0.87) | ASAH1ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL28945612 | 0.77 | ASAH1 (0.87) | ASAH1ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL28794643 | 0.76 | ASAH1 (0.70) | ASAH1ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL29795565 | 0.76 | ASAH1 (0.70) | ASAH1ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL28794596 | 0.76 | ASAH1 (0.63) | ASAH1ALDH1A1MAPTL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114787136-A | Substituted benzimidazole carboxamides and their use in the treatment of medical disorders | 比亚尔R&D投资股份公司 | 2022-07-22 | — | — | CN | disclosed |