Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 10/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29795635 | 0.87 | ASAH1 (0.87) | ASAH1POLBL3MBTL1ALDH1A1TSHR | |
| SCHEMBL28945612 | 0.87 | ASAH1 (0.87) | ASAH1POLBL3MBTL1ALDH1A1TSHR | |
| SCHEMBL29795450 | 0.85 | ASAH1 (0.69) | ASAH1POLBL3MBTL1ALDH1A1TSHR | |
| SCHEMBL28794854 | 0.85 | ASAH1 (0.69) | ASAH1POLBL3MBTL1ALDH1A1TSHR | |
| SCHEMBL29795545 | 0.85 | ASAH1 (0.62) | ASAH1POLBL3MBTL1ALDH1A1TSHR | |
| SCHEMBL28794661 | 0.84 | ASAH1 (0.67) | ASAH1POLBL3MBTL1ALDH1A1TSHR | |
| SCHEMBL28794643 | 0.84 | ASAH1 (0.70) | ASAH1POLBL3MBTL1ALDH1A1TSHR | |
| SCHEMBL29795565 | 0.84 | ASAH1 (0.70) | ASAH1POLBL3MBTL1ALDH1A1TSHR | |
| SCHEMBL29795669 | 0.81 | ASAH1 (0.84) | ASAH1POLBL3MBTL1ALDH1A1TSHR | |
| SCHEMBL28794572 | 0.81 | ASAH1 (0.84) | ASAH1POLBL3MBTL1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114787136-A | Substituted benzimidazole carboxamides and their use in the treatment of medical disorders | 比亚尔R&D投资股份公司 | 2022-07-22 | — | — | CN | disclosed |