Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 6/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29795481 | 1.00 | ASAH1 (0.70) | ASAH1L3MBTL1SMN1; SMN2ALOX15LMNA | |
| SCHEMBL28794759 | 0.96 | ASAH1 (0.64) | ASAH1L3MBTL1SMN1; SMN2ALOX15LMNA | |
| SCHEMBL29795566 | 0.96 | ASAH1 (0.64) | ASAH1L3MBTL1SMN1; SMN2ALOX15LMNA | |
| SCHEMBL29795616 | 0.86 | ASAH1 (0.57) | ASAH1SMN1; SMN2ALOX15LMNAHSD17B10 | |
| SCHEMBL28794689 | 0.86 | ASAH1 (0.57) | ASAH1SMN1; SMN2ALOX15LMNAHSD17B10 | |
| SCHEMBL29795398 | 0.83 | ASAH1 (0.93) | ASAH1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL28794797 | 0.83 | ASAH1 (0.93) | ASAH1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL10654951 | 0.83 | ASAH1 (0.90) | ASAH1SMN1; SMN2TSHRHSD17B10HPGD | |
| SCHEMBL29795633 | 0.82 | ASAH1 (1.00) | ASAH1 | |
| SCHEMBL28945621 | 0.82 | ASAH1 (1.00) | ASAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114787136-A | Substituted benzimidazole carboxamides and their use in the treatment of medical disorders | 比亚尔R&D投资股份公司 | 2022-07-22 | — | — | CN | disclosed |