Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.49 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | HTR5A | P47898 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.45 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22068158 | 0.81 | IDO1 (0.55) | MAPK10MAP4K4MINK1TNIKMAPT | |
| SCHEMBL21333215 | 0.79 | NOTUM (0.48) | MAPK10MAP4K4MINK1TNIKALDH1A1 | |
| SCHEMBL31472663 | 0.79 | NOTUM (0.48) | MAPK10MAP4K4MINK1TNIKALDH1A1 | |
| SCHEMBL25954683 | 0.78 | MAPKAPK2 (0.53) | CYP17A1CYP19A1CYP11B1CYP11B2MAPK9 | |
| SCHEMBL18703800 | 0.77 | DYRK1A (0.57) | CYP17A1CYP19A1CYP11B1CYP11B2MAPK9 | |
| SCHEMBL17445451 | 0.77 | CYP11B1 (0.50) | CYP17A1CYP19A1CYP11B1CYP11B2MAPK9 | |
| SCHEMBL16805041 | 0.77 | DYRK1A (0.58) | CYP17A1CYP19A1CYP11B1CYP11B2MAPK9 | |
| SCHEMBL30341252 | 0.76 | NPC1 (0.51) | GSK3BMAP4K4MINK1TNIKNPC1 | |
| SCHEMBL239121 | 0.76 | ESR1 (0.71) | CYP17A1CYP19A1CYP11B1CYP11B2ESR1 | |
| SCHEMBL5013872 | 0.76 | ESR1 (0.71) | CYP17A1CYP19A1CYP11B1CYP11B2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216758-A1 | Pyridone Compounds | MSD K.K. (JP) | 2010-08-26 | — | — | US | disclosed |
| EP-1916239-A1 | PYRIDONE COMPOUND | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-04-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216758-A1 | Pyridone Compounds | NPY1R, MC5R, MC1R | CYP17A1 177/4885CYP19A1 91/4885CYP11B1 71/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.