Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 15/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 10/20 | 0.46 |
| ▸ | AR | P10275 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.37 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803014 | 1.00 | CRBN (0.50) | CRBNDDB1ARMAPTALDH1A1 | |
| SCHEMBL29803123 | 0.95 | CRBN (0.46) | CRBNDDB1AR | |
| SCHEMBL28945672 | 0.95 | CRBN (0.46) | CRBNDDB1AR | |
| SCHEMBL28795206 | 0.95 | CRBN (0.54) | CRBNDDB1ARMAPTCDK9 | |
| SCHEMBL29803111 | 0.94 | CRBN (0.48) | CRBNDDB1ARGSPT1 | |
| SCHEMBL28945689 | 0.94 | CRBN (0.48) | CRBNDDB1ARGSPT1 | |
| SCHEMBL28795191 | 0.94 | CRBN (0.53) | CRBNDDB1ARCDK9BRD9 | |
| SCHEMBL28795252 | 0.92 | CRBN (0.49) | CRBNDDB1ARGSPT1 | |
| SCHEMBL28795193 | 0.91 | CRBN (0.49) | CRBNDDB1ARCDK9 | |
| SCHEMBL29802996 | 0.90 | CRBN (0.48) | CRBNDDB1ARCDK9BRD9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805303-A | Molecule with double functions of degrading EGFR (epidermal growth factor receptor), composition and pharmaceutical application thereof | 海思科医药集团股份有限公司 | 2022-07-29 | — | — | CN | disclosed |