Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexane SCHEMBL27513465 | 0.97 | TSHR (0.49) | TSHRRECQLSMN1; SMN2USP2PKM | |
| SCHEMBL15818433 | 0.83 | TSHR (0.67) | TSHRRECQLSMN1; SMN2USP2LMNA | |
| SCHEMBL15831122 | 0.83 | TSHR (0.67) | TSHRRECQLSMN1; SMN2USP2LMNA | |
| SCHEMBL7279994 | 0.80 | TSHR (0.49) | TSHRRECQLSMN1; SMN2USP2PKM | |
| SCHEMBL12206737 | 0.80 | TSHR (0.55) | TSHRRECQLSMN1; SMN2USP2PKM | |
| SCHEMBL697035 | 0.78 | TSHR (0.53) | TSHRRECQLSMN1; SMN2USP2PKM | |
| SCHEMBL296555 | 0.78 | TSHR (0.53) | TSHRRECQLSMN1; SMN2USP2PKM | |
| SCHEMBL17894913 | 0.78 | TSHR (0.53) | TSHRRECQLSMN1; SMN2USP2PKM | |
| SCHEMBL28795395 | 0.78 | TSHR (0.42) | TSHRRECQLSMN1; SMN2USP2PKM | |
| SCHEMBL208812 | 0.77 | TSHR (0.61) | TSHRRECQLSMN1; SMN2USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805340-A | Process for producing imidazopyridine compound and intermediate thereof | 武汉人福创新药物研发中心有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-114805237-A | Process for producing heterocyclic compound and intermediate thereof | 武汉人福创新药物研发中心有限公司 | 2022-07-29 | — | — | CN | disclosed |