Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | MAOB | P27338 | 6/20 | 0.60 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.60 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.57 |
| ▸ | MAOA | P21397 | 2/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.56 |
| ▸ | PPARA | Q07869 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10070189 | 0.88 | CYP1B1 (0.71) | MAPTTDP1MAOBCYP1B1KMT2A | |
| SCHEMBL16052183 | 0.88 | CYP1B1 (0.71) | MAPTTDP1MAOBCYP1B1KMT2A | |
| SCHEMBL28481451 | 0.82 | MAPT (0.68) | MAPTTDP1L3MBTL1MAOBCYP1B1 | |
| SCHEMBL10070198 | 0.82 | MAPT (0.68) | MAPTTDP1L3MBTL1MAOBCYP1B1 | |
| SCHEMBL8210174 | 0.82 | MAPT (1.00) | MAPTTDP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL1790578 | 0.82 | MAPT (0.87) | MAPTTDP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL10017454 | 0.82 | BCHE (0.81) | MAPTMAOBCYP1B1KMT2ATNFRSF1A | |
| SCHEMBL28679086 | 0.80 | MAPT (0.84) | MAPTTDP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL16051995 | 0.80 | CYP1A2 (0.70) | MAPTTDP1L3MBTL1MAOBCYP1B1 | |
| SCHEMBL16051996 | 0.80 | CYP1A2 (0.70) | MAPTTDP1L3MBTL1MAOBCYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109503351-B | Chalcone derivative containing allyl structure and application thereof | 温州医科大学 | 2022-01-04 | — | — | CN | disclosed |