⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27716493 | 1.00 | — | — | |
| SCHEMBL12488069 | 0.69 | — | — | |
| SCHEMBL7894908 | 0.68 | ESR2 (0.32) | — | |
| SCHEMBL27526976 | 0.67 | MAPT (0.30) | — | |
| SCHEMBL1571721 | 0.67 | — | — | |
| SCHEMBL9280245 | 0.66 | — | — | |
| SCHEMBL7135080 | 0.65 | — | — | |
| SCHEMBL10711146 | 0.65 | — | — | |
| SCHEMBL27619305 | 0.63 | — | — | |
| SCHEMBL7144821 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103159735-B | The imidazoles kinase inhibitor replaced | TONGHUA JIDA PHARMACEUTICAL CO., LTD. (CN) | 2015-12-09 | — | — | CN | disclosed |
| CN-104918617-A | As P2X7Heterocyclic amide derivatives of receptor antagonists | ACTELION PHARMACEUTICALS LTD | 2015-09-16 | — | — | CN | disclosed |
| CN-103159736-B | Substitutional pyrazol kinase inhibitor | TONGHUA JIDA PHARMACEUTICAL CO LTD | 2015-05-13 | — | — | CN | disclosed |
| CN-104066737-A | As P2X7Heterocyclic amide derivatives of receptor antagonists | ACTELION PHARMACEUTICALS LTD | 2014-09-24 | — | — | CN | disclosed |
| CN-103159735-A | Substitutional imidazole kinase inhibitor | TONGHUA SIHUAN PHARM CO LTD | 2013-06-19 | — | — | CN | disclosed |
| CN-103159736-A | Substitutional pyrazol kinase inhibitor | TONGHUA SIHUAN PHARM CO LTD | 2013-06-19 | — | — | CN | disclosed |
| CN-1543455-B | 3-phenoxy-4-pyridazinol derivatives and herbicidal compositions containing the same | SANKYO AGRO CO LTD | 2012-07-11 | — | — | CN | disclosed |