Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 18/20 | 1.00 |
| ▸ | APP | P05067 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28796179 | 0.92 | PTPN1 (1.00) | PTPN1APP | |
| SCHEMBL28796198 | 0.87 | PTPN1 (1.00) | PTPN1 | |
| SCHEMBL28796217 | 0.85 | PTPN1 (1.00) | PTPN1 | |
| SCHEMBL28796167 | 0.84 | PTPN1 (1.00) | PTPN1 | |
| SCHEMBL5084271 | 0.84 | APP (0.82) | PTPN1APPMEN1NPC1MAPT | |
| SCHEMBL5084266 | 0.84 | APP (0.82) | PTPN1APPMEN1NPC1MAPT | |
| SCHEMBL7189590 | 0.83 | PTPN1 (1.00) | PTPN1 | |
| SCHEMBL7189587 | 0.83 | PTPN1 (1.00) | PTPN1 | |
| SCHEMBL4446313 | 0.82 | APP (1.00) | PTPN1APPMEN1NPC1MAPT | |
| SCHEMBL4446319 | 0.82 | APP (1.00) | PTPN1APPMEN1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109503351-B | Chalcone derivative containing allyl structure and application thereof | 温州医科大学 | 2022-01-04 | — | — | CN | disclosed |