Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 3/20 | 0.43 |
| ▸ | GABRD | O14764 | 3/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.43 |
| ▸ | GABRE | P78334 | 3/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.43 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.43 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21616768 | 0.81 | MAPK1 (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL29465880 | 0.79 | MAPK1 (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL21598830 | 0.79 | MAPK1 (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28667813 | 0.79 | CD274 (0.37) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28476138 | 0.79 | MAPK1 (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28666423 | 0.76 | PDCD1 (0.38) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL21257301 | 0.73 | NPC1 (0.39) | KDM4ELMNAALDH1A1MAPTHPGD | |
| SCHEMBL31651591 | 0.71 | MAPK1 (0.45) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL21616761 | 0.71 | MAPK1 (0.45) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11030074 | 0.70 | MAPK1 (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113880833-A | Biphenyl polycyclic derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2022-01-04 | — | — | CN | disclosed |