Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL567119 | 1.00 | CA14 (0.45) | CA14SSTR4TDP1HDAC1HDAC2 | |
| SCHEMBL567990 | 0.96 | CA14 (0.47) | CA14SSTR4TDP1HDAC1HDAC2 | |
| SCHEMBL27854130 | 0.96 | CA14 (0.47) | CA14SSTR4TDP1HDAC1HDAC2 | |
| SCHEMBL567402 | 0.87 | CA14 (0.43) | CA14SSTR4TDP1HDAC1HDAC2 | |
| SCHEMBL567400 | 0.87 | CA14 (0.43) | CA14SSTR4TDP1HDAC1HDAC2 | |
| SCHEMBL567297 | 0.84 | CA14 (0.44) | CA14SSTR4TDP1HDAC1HDAC2 | |
| SCHEMBL567295 | 0.84 | CA14 (0.44) | CA14SSTR4TDP1HDAC1HDAC2 | |
| SCHEMBL567649 | 0.83 | CA14 (0.45) | CA14SSTR4TDP1HDAC1HDAC2 | |
| SCHEMBL567647 | 0.83 | CA14 (0.45) | CA14SSTR4TDP1HDAC1HDAC2 | |
| SCHEMBL16428936 | 0.80 | CA14 (0.47) | CA14SSTR4TDP1HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102448941-A | Substituted isoquinoline derivatives | WESTERN THERAPEUTICS INST INC D | 2012-05-09 | — | — | CN | disclosed |