Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 20/20 | 0.59 |
| ▸ | BCL2 | P10415 | 11/20 | 0.59 |
| ▸ | MDM4 | O15151 | 1/20 | 0.55 |
| ▸ | BCL2L11 | O43521 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | BID | P55957 | 1/20 | 0.55 |
| ▸ | BAX | Q07812 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | ASPH | Q12797 | 1/20 | 0.55 |
| ▸ | BECN1 | Q14457 | 1/20 | 0.55 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.55 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.55 |
| ▸ | BAD | Q92934 | 1/20 | 0.55 |
| ▸ | BBC3 | Q9BXH1 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1541000 | 0.86 | BCL2L1 (0.61) | BCL2L1BCL2MDM4BCL2L11TP53 | |
| SCHEMBL1540422 | 0.85 | BCL2L1 (0.61) | BCL2L1BCL2MDM4BCL2L11TP53 | |
| SCHEMBL1541445 | 0.84 | BCL2L1 (0.73) | BCL2L1BCL2MDM4BCL2L11TP53 | |
| SCHEMBL1540900 | 0.83 | BCL2L1 (0.58) | BCL2L1BCL2MDM4BCL2L11TP53 | |
| SCHEMBL1540971 | 0.82 | BCL2 (0.67) | BCL2L1BCL2 | |
| SCHEMBL1540693 | 0.82 | BCL2L1 (0.66) | BCL2L1BCL2MDM4BCL2L11TP53 | |
| SCHEMBL1540205 | 0.82 | BCL2L1 (0.60) | BCL2L1BCL2MDM4BCL2L11TP53 | |
| SCHEMBL1540274 | 0.82 | BCL2L1 (0.57) | BCL2L1BCL2MDM4BCL2L11TP53 | |
| SCHEMBL1540747 | 0.82 | BCL2L1 (0.58) | BCL2L1BCL2MDM4BCL2L11TP53 | |
| SCHEMBL1540405 | 0.81 | BCL2L1 (0.61) | BCL2L1BCL2MDM4BCL2L11TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1906183-B | N-acylsulfonamide apoptosis promoters | ABBOTT LAB | 2012-06-20 | — | — | CN | claimed |