Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 14/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.45 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28798383 | 0.91 | EGFR (0.46) | EPHA2EGFRKDREPHB4ABCG2 | |
| SCHEMBL28798373 | 0.89 | EPHA2 (0.46) | EPHA2EGFRKDREPHB4ABCG2 | |
| SCHEMBL28798422 | 0.88 | EGFR (0.48) | EPHA2EGFRKDREPHB4ABCG2 | |
| SCHEMBL28798367 | 0.87 | EPHA2 (0.50) | EPHA2EGFRKDREPHB4 | |
| SCHEMBL28798391 | 0.83 | EGFR (0.57) | EPHA2EGFRKDREPHB4ABCG2 | |
| SCHEMBL28946210 | 0.82 | EGFR (0.51) | EPHA2EGFRKDREPHB4ABCG2 | |
| SCHEMBL28829727 | 0.80 | HDAC3 (0.47) | EPHA2EGFRKDREPHB4 | |
| SCHEMBL28798345 | 0.78 | EPHA2 (0.47) | EPHA2EGFRKDREPHB4 | |
| SCHEMBL28938270 | 0.77 | EPHA2 (0.42) | EPHA2 | |
| SCHEMBL28798352 | 0.77 | EGFR (0.49) | EPHA2EGFRKDREPHB4ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114835683-A | Quinazoline-4, 6-diamine compound containing morpholinyl aromatic heterocycle and preparation method thereof | 江苏食品药品职业技术学院 | 2022-08-02 | — | — | CN | disclosed |