⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrazole SCHEMBL30854861 | 0.90 | — | — | |
| Pyrazole SCHEMBL30626480 | 0.90 | — | — | |
| Pyrazole SCHEMBL5664483 | 0.90 | — | — | |
| Pyrazole SCHEMBL1384 | 0.90 | — | — | |
| Pyrazole SCHEMBL7671561 | 0.90 | — | — | |
| Pyrazole SCHEMBL27452811 | 0.88 | — | — | |
| Pyrazole SCHEMBL23295201 | 0.87 | — | — | |
| Pyrazole SCHEMBL1800516 | 0.87 | — | — | |
| Pyrazole SCHEMBL17361377 | 0.87 | — | — | |
| Pyrazole SCHEMBL8421546 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9339033-B2 | 1-aryl-5-alkyl pyrazole derivative compounds, processes of making and methods of using thereof | MERIAL, INC. (US) | 2016-05-17 | — | — | US | disclosed |
| EP-2035390-B1 | 1-Aryl-5-alkyl pyrazole derivative compounds, processes of making and methods of using thereof | MERIAL INC (US) | 2015-12-09 | — | — | EP | disclosed |
| US-20150133506-A1 | 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF | AVENTIS AGRICULTURE (FR) | 2015-05-14 | — | — | US | disclosed |
| US-8785372-B2 | 1-aryl-5-alkyl pyrazole derivative compounds, processes of making and methods of using thereof | AVENTIS AGRICULTURE | 2014-07-22 | — | — | US | disclosed |
| US-20130324457-A1 | 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF | AVENTIS AGRICULTURE (FR) | 2013-12-05 | — | — | US | disclosed |
| US-8445519-B2 | 1-aryl-5-alkyl pyrazole derivative compounds, processes of making and methods of using thereof | AVENTIS AGRICULTURE (FR) | 2013-05-21 | — | — | US | disclosed |
| EP-2465851-A1 | 1-Aryl-5-alkyl pyrazole derivative compounds, processes of making and methods of using thereof | Aventis Agriculture (FR) | 2012-06-20 | — | — | EP | disclosed |
| US-20100249194-A1 | 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF | MERIAL, INC. | 2010-09-30 | — | — | US | disclosed |
| US-7759381-B2 | 1-aryl-5-alkyl pyrazole derivative compounds, processes of making and methods of using thereof | AVENTIS AGRICULTURE (FR) | 2010-07-20 | — | — | US | disclosed |
| EP-2035390-A2 | 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF | Aventis Agriculture (FR) | 2009-03-18 | — | — | EP | disclosed |
| US-20080031902-A1 | 1-Aryl-5-alkyl pyrazole derivative compounds, processes of making and methods of using thereof | MERIAL, INC. | 2008-02-07 | — | — | US | disclosed |
| WO-2008005489-A2 | 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF | AVENTIS AGRICULTURE (FR) | 2008-01-10 | — | — | WO | disclosed |